⚫️ Наукові дослідження та матеріали:
📚 Науковий аналіз, експериментальні та лабораторні дослідження, доказові матеріали:
👇 Spirulina (спіруліна) 🌿:
🥗🤩 Схуднення, зайва вага, ожиріння - 5 досліджень [1-5]:
- Fujimoto M, Tsuneyama K, Fujimoto T, Selmi C, Gershwin ME, Shimada YSpirulina improves non-alcoholic steatohepatitis, visceral fat macrophage aggregation, and serum leptin in a mouse model of metabolic syndromeDig Liver Dis.(2012 Sep)
- Obesity is associated with macrophage accumulation in adipose tissue.()
- Furukawa S, Fujita T, Shimabukuro M, Iwaki M, Yamada Y, Nakajima Y, Nakayama O, Makishima M, Matsuda M, Shimomura IIncreased oxidative stress in obesity and its impact on metabolic syndromeJ Clin Invest.(2004 Dec)
- Iwatsuka H, Shino A, Suzuoki ZGeneral survey of diabetic features of yellow KK miceEndocrinol Jpn.(1970 Feb)
- Ou Y, Lin L, Yang X, Pan Q, Cheng XAntidiabetic potential of phycocyanin: Effects on KKAy micePharm Biol.(2013 May)
🌿🧹 Детокс, очищення організму, антиоксидант, закислення організму, окислення ліпідів, важкі метали, неврологія, нейротоксичність, тестостерон, алергії, захворювання шкіри, меланома - 36 досліджень [5-41]:
- Doshi H, Ray A, Kothari ILBiosorption of cadmium by live and dead Spirulina: IR spectroscopic, kinetics, and SEM studiesCurr Microbiol.(2007 Mar)
- Solisio C, Lodi A, Soletto D, Converti ACadmium biosorption on Spirulina platensis biomassBioresour Technol.(2008 Sep)
- Cain A, Vannela R, Woo LKCyanobacteria as a biosorbent for mercuric ionBioresour Technol.(2008 Sep)
- Fang L, Zhou C, Cai P, Chen W, Rong X, Dai K, Liang W, Gu JD, Huang QBinding characteristics of copper and cadmium by cyanobacterium Spirulina platensisJ Hazard Mater.(2011 Jun 15)
- Saha SK, Misbahuddin M, Ahmed AUComparison between the effects of alcohol and hexane extract of spirulina in arsenic removal from isolated tissuesMymensingh Med J.(2010 Jan)
- Saha SK, Misbahuddin M, Khatun R, Mamun IREffect of hexane extract of spirulina in the removal of arsenic from isolated liver tissues of ratMymensingh Med J.(2005 Jul)
- Banji D, Banji OJ, Pratusha NG, Annamalai ARInvestigation on the role of Spirulina platensis in ameliorating behavioural changes, thyroid dysfunction and oxidative stress in offspring of pregnant rats exposed to fluorideFood Chem.(2013 Sep 1)
- Gargouri M, Ghorbel-Koubaa F, Bonenfant-Magné M, Magné C, Dauvergne X, Ksouri R, Krichen Y, Abdelly C, El Feki ASpirulina or dandelion-enriched diet of mothers alleviates lead-induced damages in brain and cerebellum of newborn ratsFood Chem Toxicol.(2012 Jul)
- Paniagua-Castro N, Escalona-Cardoso G, Hernández-Navarro D, Pérez-Pastén R, Chamorro-Cevallos GSpirulina (Arthrospira) protects against cadmium-induced teratogenic damage in miceJ Med Food.(2011 Apr)
- El-Desoky GE, Bashandy SA, Alhazza IM, Al-Othman ZA, Aboul-Soud MA, Yusuf KImprovement of Mercuric Chloride-Induced Testis Injuries and Sperm Quality Deteriorations by Spirulina platensis in RatsPLoS One.(2013)
- Sharma MK, Sharma A, Kumar A, Kumar MEvaluation of protective efficacy of Spirulina fusiformis against mercury induced nephrotoxicity in Swiss albino miceFood Chem Toxicol.(2007 Jun)
- Madhyastha HK, Radha KS, Sugiki M, Omura S, Maruyama MPurification of c-phycocyanin from Spirulina fusiformis and its effect on the induction of urokinase-type plasminogen activator from calf pulmonary endothelial cellsPhytomedicine.(2006 Sep)
- Saxena PS, Kumar MModulatory potential of Spirulina fusiformis on testicular phosphatases in Swiss albino mice against mercury intoxicationIndian J Exp Biol.(2004 Oct)
- Sharma MK, Patni R, Kumar M, Kumar AModification of mercury-induced biochemical alterations in blood of Swiss albino mice by Spirulina fusiformisEnviron Toxicol Pharmacol.(2005 Sep)
- Simsek N, Karadeniz A, Kalkan Y, Keles ON, Unal BSpirulina platensis feeding inhibited the anemia- and leucopenia-induced lead and cadmium in ratsJ Hazard Mater.(2009 May 30)
- Karadeniz A, Cemek M, Simsek NThe effects of Panax ginseng and Spirulina platensis on hepatotoxicity induced by cadmium in ratsEcotoxicol Environ Saf.(2009 Jan)
- Jeyaprakash K, Chinnaswamy PEffect of spirulina and Liv-52 on cadmium induced toxicity in albino ratsIndian J Exp Biol.(2005 Sep)
- Jeyaprakash K, Chinnaswamy PHypocholesterolaemic effect of spirulina and liv-52 in lead induced toxicity in albino ratsAnc Sci Life.(2004 Oct)
- Misbahuddin M, Islam AZ, Khandker S, Ifthaker-Al-Mahmud, Islam N, AnjumanaraEfficacy of spirulina extract plus zinc in patients of chronic arsenic poisoning: a randomized placebo-controlled studyClin Toxicol (Phila).(2006)
- Savranoglub S, Tumer TBInhibitory Effects of Spirulina platensis on Carcinogen-Activating Cytochrome P450 Isozymes and Potential for Drug InteractionsInt J Toxicol.(2013 Sep 30)
- McCarty MFClinical potential of Spirulina as a source of phycocyanobilinJ Med Food.(2007 Dec)
- Terry MJ, Maines MD, Lagarias JCInactivation of phytochrome- and phycobiliprotein-chromophore precursors by rat liver biliverdin reductaseJ Biol Chem.(1993 Dec 15)
- Riss J, Décordé K, Sutra T, Delage M, Baccou JC, Jouy N, Brune JP, Oréal H, Cristol JP, Rouanet JMPhycobiliprotein C-phycocyanin from Spirulina platensis is powerfully responsible for reducing oxidative stress and NADPH oxidase expression induced by an atherogenic diet in hamstersJ Agric Food Chem.(2007 Sep 19)
- Pabon MM, Jernberg JN, Morganti J, Contreras J, Hudson CE, Klein RL, Bickford PCA Spirulina-Enhanced Diet Provides Neuroprotection in an α-Synuclein Model of Parkinson's DiseasePLoS One.(2012)
- Cardona AE, Pioro EP, Sasse ME, Kostenko V, Cardona SM, Dijkstra IM, Huang D, Kidd G, Dombrowski S, Dutta R, Lee JC, Cook DN, Jung S, Lira SA, Littman DR, Ransohoff RMControl of microglial neurotoxicity by the fractalkine receptorNat Neurosci.(2006 Jul)
- CX3CL1 reduces neurotoxicity and microglial activation in a rat model of Parkinson's disease.()
- Cingi C, Conk-Dalay M, Cakli H, Bal CThe effects of spirulina on allergic rhinitisEur Arch Otorhinolaryngol.(2008 Oct)
- Mao TK, Van de Water J, Gershwin MEEffects of a Spirulina-based dietary supplement on cytokine production from allergic rhinitis patientsJ Med Food.(2005 Spring)
- Park HJ, Lee YJ, Ryu HK, Kim MH, Chung HW, Kim WYA randomized double-blind, placebo-controlled study to establish the effects of spirulina in elderly KoreansAnn Nutr Metab.(2008)
- Chu WL, Lim YW, Radhakrishnan AK, Lim PEProtective effect of aqueous extract from Spirulina platensis against cell death induced by free radicalsBMC Complement Altern Med.(2010 Sep 21)
- Shyam R, Singh SN, Vats P, Singh VK, Bajaj R, Singh SB, Banerjee PKWheat grass supplementation decreases oxidative stress in healthy subjects: a comparative study with spirulinaJ Altern Complement Med.(2007 Oct)
- Chamorro-Cevallos G, Garduño-Siciliano L, Barrón BL, Madrigal-Bujaidar E, Cruz-Vega DE, Pages NChemoprotective effect of Spirulina (Arthrospira) against cyclophosphamide-induced mutagenicity in miceFood Chem Toxicol.(2008 Feb)
- Hassan AM, Abdel-Aziem SH, Abdel-Wahhab MAModulation of DNA damage and alteration of gene expression during aflatoxicosis via dietary supplementation of Spirulina (Arthrospira) and Whey protein concentrateEcotoxicol Environ Saf.(2012 May)
- Deryagina VP, Ryzhova NI, Golubkina NAProduction of nitrogen oxide derivatives under the influence of NO-synthase inhibitors and natural compounds in mice with transplanted tumorsExp Oncol.(2012)
- Mathew B, Sankaranarayanan R, Nair PP, Varghese C, Somanathan T, Amma BP, Amma NS, Nair MKEvaluation of chemoprevention of oral cancer with Spirulina fusiformisNutr Cancer.(1995)
- Mishima T, Murata J, Toyoshima M, Fujii H, Nakajima M, Hayashi T, Kato T, Saiki IInhibition of tumor invasion and metastasis by calcium spirulan (Ca-SP), a novel sulfated polysaccharide derived from a blue-green alga, Spirulina platensisClin Exp Metastasis.(1998 Aug)
🏋️💪 Спортивні показники, спорт, витривалість, гіпертрофія, м'язи, спортивні показники, чоловіче здоров'я, гормон росту, анаболізм - 6 досліджень [41-47]:
- Voltarelli FA, de Mello MASpirulina enhanced the skeletal muscle protein in growing ratsEur J Nutr.(2008 Oct)
- Efficacy of Spirulina Supplementation on Isometric Strength and Isometric Endurance of Quadriceps in Trained and Untrained Individuals – a comparative study.()
- Lu HK, Hsieh CC, Hsu JJ, Yang YK, Chou HNPreventive effects of Spirulina platensis on skeletal muscle damage under exercise-induced oxidative stressEur J Appl Physiol.(2006 Sep)
- Torres-Durán PV, Ferreira-Hermosillo A, Ramos-Jiménez A, Hernández-Torres RP, Juárez-Oropeza MAEffect of Spirulina maxima on postprandial lipemia in young runners: a preliminary reportJ Med Food.(2012 Aug)
- Kalafati M, Jamurtas AZ, Nikolaidis MG, Paschalis V, Theodorou AA, Sakellariou GK, Koutedakis Y, Kouretas DErgogenic and antioxidant effects of spirulina supplementation in humansMed Sci Sports Exerc.(2010 Jan)
- Baicus C, Baicus ASpirulina did not ameliorate idiopathic chronic fatigue in four N-of-1 randomized controlled trialsPhytother Res.(2007 Jun)
🦠 Імунітет, рак, пухлини, онкозахворювання, Т-клітини, профілактика онкозахворювань, запалення, інфекції, вірусні захворювання, окислення, клітини-кілери - 22 дослідження [47-69]:
- Nielsen CH, Balachandran P, Christensen O, Pugh ND, Tamta H, Sufka KJ, Wu X, Walsted A, Schjørring-Thyssen M, Enevold C, Pasco DSEnhancement of natural killer cell activity in healthy subjects by Immulina®, a Spirulina extract enriched for Braun-type lipoproteinsPlanta Med.(2010 Nov)
- Lipoprotein is a predominant Toll-like receptor 2 ligand in Staphylococcus aureus cell wall components.()
- Balachandran P, Pugh ND, Ma G, Pasco DSToll-like receptor 2-dependent activation of monocytes by Spirulina polysaccharide and its immune enhancing action in miceInt Immunopharmacol.(2006 Dec 5)
- Ku CS, Pham TX, Park Y, Kim B, Shin MS, Kang I, Lee JEdible blue-green algae reduce the production of pro-inflammatory cytokines by inhibiting NF-κB pathway in macrophages and splenocytesBiochim Biophys Acta.(2013 Apr)
- Pugh N, Ross SA, ElSohly HN, ElSohly MA, Pasco DSIsolation of three high molecular weight polysaccharide preparations with potent immunostimulatory activity from Spirulina platensis, aphanizomenon flos-aquae and Chlorella pyrenoidosaPlanta Med.(2001 Nov)
- SCN Signs Major World-Wide Distribution Agreement for Patented Immune Product.()
- Grzanna R, Polotsky A, Phan PV, Pugh N, Pasco D, Frondoza CGImmolina, a high-molecular-weight polysaccharide fraction of Spirulina, enhances chemokine expression in human monocytic THP-1 cellsJ Altern Complement Med.(2006 Jun)
- DuBois RN, Radhika A, Reddy BS, Entingh AJIncreased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumorsGastroenterology.(1996 Apr)
- Saini MK, Sanyal SNPTEN regulates apoptotic cell death through PI3-K/Akt/GSK3β signaling pathway in DMH induced early colon carcinogenesis in ratExp Mol Pathol.(2012 Aug)
- Reddy MC, Subhashini J, Mahipal SV, Bhat VB, Srinivas Reddy P, Kiranmai G, Madyastha KM, Reddanna PC-Phycocyanin, a selective cyclooxygenase-2 inhibitor, induces apoptosis in lipopolysaccharide-stimulated RAW 264.7 macrophagesBiochem Biophys Res Commun.(2003 May 2)
- Reddy CM, Bhat VB, Kiranmai G, Reddy MN, Reddanna P, Madyastha KMSelective inhibition of cyclooxygenase-2 by C-phycocyanin, a biliprotein from Spirulina platensisBiochem Biophys Res Commun.(2000 Nov 2)
- Shih CM, Cheng SN, Wong CS, Kuo YL, Chou TCAntiinflammatory and antihyperalgesic activity of C-phycocyaninAnesth Analg.(2009 Apr)
- Nemoto-Kawamura C, Hirahashi T, Nagai T, Yamada H, Katoh T, Hayashi OPhycocyanin enhances secretary IgA antibody response and suppresses allergic IgE antibody response in mice immunized with antigen-entrapped biodegradable microparticlesJ Nutr Sci Vitaminol (Tokyo).(2004 Apr)
- Hirahashi T, Matsumoto M, Hazeki K, Saeki Y, Ui M, Seya TActivation of the human innate immune system by Spirulina: augmentation of interferon production and NK cytotoxicity by oral administration of hot water extract of Spirulina platensisInt Immunopharmacol.(2002 Mar)
- Akao Y, Ebihara T, Masuda H, Saeki Y, Akazawa T, Hazeki K, Hazeki O, Matsumoto M, Seya TEnhancement of antitumor natural killer cell activation by orally administered Spirulina extract in miceCancer Sci.(2009 Aug)
- Akazawa T, Ebihara T, Okuno M, Okuda Y, Shingai M, Tsujimura K, Takahashi T, Ikawa M, Okabe M, Inoue N, Okamoto-Tanaka M, Ishizaki H, Miyoshi J, Matsumoto M, Seya TAntitumor NK activation induced by the Toll-like receptor 3-TICAM-1 (TRIF) pathway in myeloid dendritic cellsProc Natl Acad Sci U S A.(2007 Jan 2)
- Pak W, Takayama F, Mine M, Nakamoto K, Kodo Y, Mankura M, Egashira T, Kawasaki H, Mori AAnti-oxidative and anti-inflammatory effects of spirulina on rat model of non-alcoholic steatohepatitisJ Clin Biochem Nutr.(2012 Nov)
- Joventino IP, Alves HG, Neves LC, Pinheiro-Joventino F, Leal LK, Neves SA, Ferreira FV, Brito GA, Viana GBThe microalga Spirulina platensis presents anti-inflammatory action as well as hypoglycemic and hypolipidemic properties in diabetic ratsJ Complement Integr Med.(2012 Aug 10)
- Hernández-Corona A, Nieves I, Meckes M, Chamorro G, Barron BLAntiviral activity of Spirulina maxima against herpes simplex virus type 2Antiviral Res.(2002 Dec)
- Yakoot M, Salem ASpirulina platensis versus silymarin in the treatment of chronic hepatitis C virus infection. A pilot randomized, comparative clinical trialBMC Gastroenterol.(2012 Apr 12)
- Băicuş C, Tănăsescu CChronic viral hepatitis, the treatment with spiruline for one month has no effect on the aminotransferasesRom J Intern Med.(2002)
- Teas J, Irhimeh MRDietary algae and HIV/AIDS: proof of concept clinical dataJ Appl Phycol.(2012 Jun)
❤️ Серцево-судинне здоров'я: серце, судини, артерії, вени, атеросклероз, варикоз, холестерин, тромбоз, ліпіди, міокард, антикоагулянт, розрідження крові, регулювання глюкози (цукру) в крові, цукровий діабет, предіабет, інсулінорезистентність, профілактика діабету - 14 дослідження [69-83]:
- Huang H, Liao D, Pu R, Cui YQuantifying the effects of spirulina supplementation on plasma lipid and glucose concentrations, body weight, and blood pressureDiabetes Metab Syndr Obes.(2018 Nov 14)
- Carrizzo A, Conte GM, Sommella E, Damato A, Ambrosio M, Sala M, Scala MC, Aquino RP, De Lucia M, Madonna M, Sansone F, Ostacolo C, Capunzo M, Migliarino S, Sciarretta S, Frati G, Campiglia P, Vecchione CNovel Potent Decameric Peptide of Spirulina platensis Reduces Blood Pressure Levels Through a PI3K/AKT/eNOS-Dependent MechanismHypertension.(2019 Feb)
- Juárez-Oropeza MA, Mascher D, Torres-Durán PV, Farias JM, Paredes-Carbajal MCEffects of dietary Spirulina on vascular reactivityJ Med Food.(2009 Feb)
- Brito AF, Silva AS, de Souza AA, Ferreira PB, de Souza ILL, Araujo LCDC, Félix GDS, Sampaio RS, Silva MDCC, Tavares RL, Pereira RA, Miranda Neto M, da Silva BAAortic Response to Strength Training and Spirulina platensis Dependent on Nitric Oxide and AntioxidantsFront Physiol.(2018 Oct 31)
- Hsiao G, Chou PH, Shen MY, Chou DS, Lin CH, Sheu JRC-phycocyanin, a very potent and novel platelet aggregation inhibitor from Spirulina platensisJ Agric Food Chem.(2005 Oct 5)
- Patricia Victoria Torres-Durán, Aldo Ferreira-Hermosillo, Arnulfo Ramos-Jiménez, Rosa Patricia Hernández-Torres, Marco Antonio Juárez-OropezaEffect of Spirulina maxima on postprandial lipemia in young runners: a preliminary reportJ Med Food.(2012 Aug)
- Nagaoka S, Shimizu K, Kaneko H, Shibayama F, Morikawa K, Kanamaru Y, Otsuka A, Hirahashi T, Kato TA novel protein C-phycocyanin plays a crucial role in the hypocholesterolemic action of Spirulina platensis concentrate in ratsJ Nutr.(2005 Oct)
- Serban MC, Sahebkar A, Dragan S, Stoichescu-Hogea G, Ursoniu S, Andrica F, Banach MA systematic review and meta-analysis of the impact of Spirulina supplementation on plasma lipid concentrationsClin Nutr.(2016 Aug)
- Szulinska M, Gibas-Dorna M, Miller-Kasprzak E, Suliburska J, Miczke A, Walczak-Gałezewska M, Stelmach-Mardas M, Walkowiak J, Bogdanski PSpirulina maxima improves insulin sensitivity, lipid profile, and total antioxidant status in obese patients with well-treated hypertension: a randomized double-blind placebo-controlled studyEur Rev Med Pharmacol Sci.(2017 May)
- Marcel AK, Ekali LG, Eugene S, Arnold OE, Sandrine ED, von der Weid D, Gbaguidi E, Ngogang J, Mbanya JCThe effect of Spirulina platensis versus soybean on insulin resistance in HIV-infected patients: a randomized pilot studyNutrients.(2011 Jul)
- Vigouroux C, Gharakhanian S, Salhi Y, Nguyên TH, Adda N, Rozenbaum W, Capeau JAdverse metabolic disorders during highly active antiretroviral treatments (HAART) of HIV diseaseDiabetes Metab.(1999 Nov)
- Parikh P, Mani U, Iyer URole of Spirulina in the Control of Glycemia and Lipidemia in Type 2 Diabetes MellitusJ Med Food.(2001 Winter)
- Kaur K, Sachdeva R, Grover KEffect of supplementation of spirulina on blood glucose and lipid profile of the non-insulin dependent diabetic male subjectsAsian Journal of Dairy and Food Research.(2008)
- Lee EH, Park JE, Choi YJ, Huh KB, Kim WYA randomized study to establish the effects of spirulina in type 2 diabetes mellitus patientsNutr Res Pract.(2008 Winter)
🧠🛡️ Захист нейронів, нейропротекція, відновлення нейронів, нейрогенез, депресія - 31 дослідження [83-114]:
- Rimbau V, Camins A, Romay C, González R, Pallàs MProtective effects of C-phycocyanin against kainic acid-induced neuronal damage in rat hippocampusNeurosci Lett.(1999 Dec 3)
- Patel M, Li QY, Chang LY, Crapo J, Liang LPActivation of NADPH oxidase and extracellular superoxide production in seizure-induced hippocampal damageJ Neurochem.(2005 Jan)
- Lanone S, Bloc S, Foresti R, Almolki A, Taillé C, Callebert J, Conti M, Goven D, Aubier M, Dureuil B, El-Benna J, Motterlini R, Boczkowski JBilirubin decreases nos2 expression via inhibition of NAD(P)H oxidase: implications for protection against endotoxic shock in ratsFASEB J.(2005 Nov)
- Chamorro G, Pérez-Albiter M, Serrano-García N, Mares-Sámano JJ, Rojas PSpirulina maxima pretreatment partially protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicityNutr Neurosci.(2006 Oct-Dec)
- Strömberg I, Gemma C, Vila J, Bickford PCBlueberry- and spirulina-enriched diets enhance striatal dopamine recovery and induce a rapid, transient microglia activation after injury of the rat nigrostriatal dopamine systemExp Neurol.(2005 Dec)
- Wu DC, Teismann P, Tieu K, Vila M, Jackson-Lewis V, Ischiropoulos H, Przedborski SNADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's diseaseProc Natl Acad Sci U S A.(2003 May 13)
- Tieu K, Ischiropoulos H, Przedborski SNitric oxide and reactive oxygen species in Parkinson's diseaseIUBMB Life.(2003 Jun)
- Zhang W, Wang T, Qin L, Gao HM, Wilson B, Ali SF, Zhang W, Hong JS, Liu BNeuroprotective effect of dextromethorphan in the MPTP Parkinson's disease model: role of NADPH oxidaseFASEB J.(2004 Mar)
- Choi DH, Cristóvão AC, Guhathakurta S, Lee J, Joh TH, Beal MF, Kim YSNADPH oxidase 1-mediated oxidative stress leads to dopamine neuron death in Parkinson's diseaseAntioxid Redox Signal.(2012 May 15)
- Thaakur SR, Jyothi BEffect of spirulina maxima on the haloperidol induced tardive dyskinesia and oxidative stress in ratsJ Neural Transm.(2007 Sep)
- Subramanyam B, Rollema H, Woolf T, Castagnoli N JrIdentification of a potentially neurotoxic pyridinium metabolite of haloperidol in ratsBiochem Biophys Res Commun.(1990 Jan 15)
- Eyles DW, McGrath JJ, Pond SMFormation of pyridinium species of haloperidol in human liver and brainPsychopharmacology (Berl).(1996 Jun)
- Thaakur S, Sravanthi RNeuroprotective effect of Spirulina in cerebral ischemia-reperfusion injury in ratsJ Neural Transm.(2010 Sep)
- Wang Y, Chang CF, Chou J, Chen HL, Deng X, Harvey BK, Cadet JL, Bickford PCDietary supplementation with blueberries, spinach, or spirulina reduces ischemic brain damageExp Neurol.(2005 May)
- Pentón-Rol G, Marín-Prida J, Pardo-Andreu G, Martínez-Sánchez G, Acosta-Medina EF, Valdivia-Acosta A, Lagumersindez-Denis N, Rodríguez-Jiménez E, Llópiz-Arzuaga A, López-Saura PA, Guillén-Nieto G, Pentón-Arias EC-Phycocyanin is neuroprotective against global cerebral ischemia/reperfusion injury in gerbilsBrain Res Bull.(2011 Aug 10)
- Bermejo-Bescós P, Piñero-Estrada E, Villar del Fresno AMNeuroprotection by Spirulina platensis protean extract and phycocyanin against iron-induced toxicity in SH-SY5Y neuroblastoma cellsToxicol In Vitro.(2008 Sep)
- McCarty MF, Barroso-Aranda J, Contreras FOral phycocyanobilin may diminish the pathogenicity of activated brain microglia in neurodegenerative disordersMed Hypotheses.(2010 Mar)
- George S, Rey NL, Reichenbach N, Steiner JA, Brundin Pα-Synuclein: The Long Distance RunnerBrain Pathol.(2013 May)
- Lehéricy S, Sharman MA, Dos Santos CL, Paquin R, Gallea CMagnetic resonance imaging of the substantia nigra in Parkinson's diseaseMov Disord.(2012 Jun)
- Surmeier DJ, Guzman JN, Sanchez-Padilla J, Schumacker PTThe role of calcium and mitochondrial oxidant stress in the loss of substantia nigra pars compacta dopaminergic neurons in Parkinson's diseaseNeuroscience.(2011 Dec 15)
- Guo JP, Yu S, McGeer PLSimple in vitro assays to identify amyloid-beta aggregation blockers for Alzheimer's disease therapyJ Alzheimers Dis.(2010)
- Hwang JH, Lee IT, Jeng KC, Wang MF, Hou RC, Wu SM, Chan YCSpirulina prevents memory dysfunction, reduces oxidative stress damage and augments antioxidant activity in senescence-accelerated miceJ Nutr Sci Vitaminol (Tokyo).(2011)
- Alpha-synuclein release by neurons activates the inflammatory response in a microglial cell line.()
- Zhang QG, Laird MD, Han D, Nguyen K, Scott E, Dong Y, Dhandapani KM, Brann DWCritical role of NADPH oxidase in neuronal oxidative damage and microglia activation following traumatic brain injuryPLoS One.(2012)
- Chen JC, Liu KS, Yang TJ, Hwang JH, Chan YC, Lee ITSpirulina and C-phycocyanin reduce cytotoxicity and inflammation-related genes expression of microglial cellsNutr Neurosci.(2012 Jun 7)
- Patro N, Sharma A, Kariaya K, Patro ISpirulina platensis protects neurons via suppression of glial activation and peripheral sensitization leading to restoration of motor function in collagen-induced arthritic ratsIndian J Exp Biol.(2011 Oct)
- Gemma C, Mesches MH, Sepesi B, Choo K, Holmes DB, Bickford PCDiets enriched in foods with high antioxidant activity reverse age-induced decreases in cerebellar beta-adrenergic function and increases in proinflammatory cytokinesJ Neurosci.(2002 Jul 15)
- Spirulina Promotes Stem Cell Genesis and Protects against LPS Induced Declines in Neural Stem Cell Proliferation.()
- Short Communication: Neuroprotective Effect of Spirulina in a Mouse Model of ALS.()
- ALSUntangled GroupALSUntangled No. 9: Blue-green algae (Spirulina) as a treatment for ALSAmyotroph Lateral Scler.(2011 Mar)
- Kim NH, Jeong HJ, Lee JY, Go H, Ko SG, Hong SH, Kim HM, Um JYThe effect of hydrolyzed Spirulina by malted barley on forced swimming test in ICR miceInt J Neurosci.(2008 Nov)
🦴 Кістки, суглоби, біль в суглобах, артрит, артроз, хрящі - 5 досліджень [114-119]:
- Ishimi Y, Sugiyama F, Ezaki J, Fujioka M, Wu JEffects of spirulina, a blue-green alga, on bone metabolism in ovariectomized rats and hindlimb-unloaded miceBiosci Biotechnol Biochem.(2006 Feb)
- Gitte S Jensen, Cassandra Drapeau, Miki Lenninger, Kathleen F BensonClinical Safety of a High Dose of Phycocyanin-Enriched Aqueous Extract from Arthrospira (Spirulina) platensis: Results from a Randomized, Double-Blind, Placebo-Controlled Study with a Focus on Anticoagulant Activity and Platelet ActivationJ Med Food.(2016 Jul)
- Kumar N, Singh S, Patro N, Patro IEvaluation of protective efficacy of Spirulina platensis against collagen-induced arthritis in ratsInflammopharmacology.(2009 Jun)
- Rasool M, Sabina EP, Lavanya BAnti-inflammatory effect of Spirulina fusiformis on adjuvant-induced arthritis in miceBiol Pharm Bull.(2006 Dec)
- Remirez D, González R, Merino N, Rodriguez S, Ancheta OInhibitory effects of Spirulina in zymosan-induced arthritis in miceMediators Inflamm.(2002 Apr)
🍽️ ШКТ, шлунок, кишечник (кишківник) - 4 дослідження [119-123]:
- DuBois RN, Radhika A, Reddy BS, Entingh AJIncreased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumorsGastroenterology.(1996 Apr)
- Saini MK, Sanyal SNPTEN regulates apoptotic cell death through PI3-K/Akt/GSK3β signaling pathway in DMH induced early colon carcinogenesis in ratExp Mol Pathol.(2012 Aug)
- Saini MK, Sanyal SN, Vaiphei KPiroxicam and C-phycocyanin mediated apoptosis in 1,2-dimethylhydrazine dihydrochloride induced colon carcinogenesis: exploring the mitochondrial pathwayNutr Cancer.(2012 Apr)
- Saini MK, Vaiphei K, Sanyal SNChemoprevention of DMH-induced rat colon carcinoma initiation by combination administration of piroxicam and C-phycocyaninMol Cell Biochem.(2012 Feb)
🍔 Печінка - 13 досліджень [123-136]:
- Bhattacharyya S, Mehta PThe hepatoprotective potential of Spirulina and vitamin C supplemention in cisplatin toxicityFood Funct.(2012 Feb)
- Lu J, Ren DF, Wang JZ, Sanada H, Egashira YProtection by dietary Spirulina platensis against D-galactosamine--and acetaminophen-induced liver injuriesBr J Nutr.(2010 Jun)
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🚰 Нирки - 6 досліджень [136-142]:
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